The preliminary effects of Serum Amniotique E on my skin, after 63 days, has smoothed out my fine lines but not diminished them; its hydrating quality has given my overall appearance the beginnings of a softer look. I use the serum in conjunction to Lait Vip O2, P50 Original, Serum Placenta, Creme Amnios (am) and Creme Placenta (pm). My skin feels a lot better than before using Biologique Recherche products. I love the texture of the serum and it goes on smoothly, not evaporating while applying. Serum Amniotique E is a great first step to attacking fine lines, wrinkles, and dehydrated skin. While I enjoyed using it, I look forward to taking the next step with Serum Colostrum.